Analysis of telomere length in couples experiencing idiopathic recurrent pregnancy loss

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Molecular Mechanisms of Recurrent Pregnancy Loss

Introduction: Pregnancy and health is the process in which the egg is fertilized and being able to survive. When pregnancy occurs under some conditions and the fetus is being at risk, it will lead to abortion that occurs involuntarily and spontaneously. Abortions that occur more than two or three times are called recurrent pregnancy loss (RPL). Various etiological factors involved in RPL, inclu...

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Introduction: Abortion is a common complication that refers to the early termination of pregnancy with the death of the fetus before the 20th week of pregnancy. Previous studies show that many genes are involved in this disease, including the CX3CR1 gene, which is one of the inflammatory response genes in the immune system. The pathogenicity of these variants was determined in this study using ...

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The Effect of HLA-DRB1 Sharing between the Couples with Recurrent Pregnancy Loss on the Pregnancy Outcome after Leukocyte Therapy

Background: Miscarriage is a common phenomenon complicating more than half of pregnancies. Recurrent Pregnancy Loss (RPL) is defined as three or more pregnancies lost before the twentieth week of gestation. It is believed that abnormality in maternal immune reaction to fetus and sharing of HLA antigens might be associated with RPL. Objective: To investigate the effect of HLA-DRB1 sharing betwee...

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I-24: New Molecular Aspects in Recurrent Pregnancy Loss

Background Recurrent pregnancy loss (RPL) is usually defined as three or more consecutive pregnancy losses before 20th gestational week. Many etiological factors have been considered as cause of RPL including genetic factors, uterine anatomical defects, endocrine abnormalities, thrombotic and immunologic factors. Nevertheless, the cause of RPL remains unknown in around half of the patients desp...

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Background Accurate prevalence figures are not available, but it has been estimated that 1-2% of women have recurrent pregnancy loss (RPL), defined as three or more consecutive losses of intrauterine pregnancy in the first trimester. Half of whom have no identifiable cause. Recent studies of early pregnancy loss, preeclampsia, pregnancy complications such a hydatidiform mole suggests that these...

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ژورنال

عنوان ژورنال: Journal of Assisted Reproduction and Genetics

سال: 2013

ISSN: 1058-0468,1573-7330

DOI: 10.1007/s10815-013-9993-1